The 2-Minute Rule for cees dekker

The 2-Minute Rule for cees dekker

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‘The 2nd is nanopores, which happens to be our oldest line of research and that has now led to DNA sequencers depending on nanopores. We pull specific DNA strands by way of a nanopore and may then go through off the nucleotide sequence. Extremely not too long ago, we even managed to study out a single protein for the first time applying This system. But this line of investigation is not merely about building tools, but additionally about genuine Organic issues.

Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules

Being a individual, I possess the biblical assignment to check out and use all the things in creation for the advantage of my neighbour. I will not experience any conflict among religion and science. Quite the opposite, my religion stimulates me to do science, for being open-minded on the earth.’

I can rarely consider how I, for a geneticist, would have the capacity to study elementary physics, let alone compete at the highest. How did you go about this?

2015, discovery that condensin is actually a highly adaptable protein construction; and initial detection of DNA knots applying nanopores

The coiled-coil from the human Rad50 DNA maintenance protein is made up of particular segments of amplified overall flexibility

Given that 2000 he moved to single-molecule biophysics and nanobiology, with investigate from DNA supercoiling scientific tests of nucleosomes and DNA mend proteins to DNA translocation by means of nanopores. Lately his research has centered on learning cell division with micro organism on chip, when his final interest is during the route of recognizing artificial cells.

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At this time, we cees dekker also understood that it ought to be probable to employ only one semiconducting carbon nanotube to help make a transistor — and we established out to really make it. We stretched personal semiconducting nanotubes across metallic electrodes and utilized the underlying silicon substrate to be a gate electrode, creating The fundamental 3-terminal layout of the industry-influence transistor (Fig.

FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division

2006, very first demonstration of molecular sorting in a very lab with a chip making use of biomotors; discovery of nanobubbles in stable-point out nanopores; and initial estimate of electrokinetic Strength conversion inside of a nanofluidic channel

Visualization of unstained DNA nanostructures with Innovative in-aim transmission electron microscopy techniques

Sound-condition nanopores have verified for being a incredibly adaptable probe for solitary-molecule Examination of DNA. I'll describe many of our current findings – exclusively DNA knots – together with our initiatives to develop the abilities of reliable-condition nanopores even more, inside the route of single-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.